Dr. Christoph Westphal is co-founder and General Partner of Longwood Fund and has spent 20 years as a life sciences CEO, entrepreneur, and investor. Christoph has been the co-founder, CEO, and lead investor of six biotechnology companies that have completed initial public offerings (IPOs) and have developed and received FDA approval for important drugs. These include: Momenta Pharmaceuticals, Inc. (NASDAQ: MNTA), Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY), Acceleron Pharma, Inc. (NASDAQ: XLRN), Sirtris Pharmaceuticals, Inc. (NASDAQ: SIRT, acquired by GSK in 2008), and Verastem (NASDAQ: VSTM). Christoph is also co-founder of Longwood portfolio companies Alnara Pharmaceuticals (acquired by Eli Lilly), Axial Biotherapeutics, TScan Therapeutics, Immunitas Therapeutics, and Pyxis Oncology, and co-founder of Concert Pharmaceuticals (NASDAQ: CNCE).
Companies founded by Christoph have developed and received FDA approval for important drugs, including the first RNAi therapy; for currently incurable cancers; the largest-selling heparin in the United States; a therapy for MS; for Beta Thalassemia and Myelodysplastic Syndrome; and several experimental medicines for cystic fibrosis (Phase III), serious inflammatory disorders (Phase II), and serious neurological illnesses such as ALS and MS (positive Phase II).
Christoph earned his M.D. from Harvard Medical School and Ph.D. in genetics from Harvard University; and he graduated with a B.A. summa cum laude and Phi Beta Kappa from Columbia University. He has served or currently serves as a member or director of the Boston Commercial Club, the Biotechnology Industry Organization’s (BIO) Emerging Companies Section Governing Board, the Board of Fellows of Harvard Medical School, and the Board of Trustees of the Boston Symphony Orchestra. Christoph has been the lead or senior author on several patent applications and scientific papers in journals such as Cell, Nature, and Nature Genetics. Christoph has been featured on 60 Minutes with Morley Safer, CNN’s Vital Signs with Dr. Sanjay Gupta, an ABC News Special hosted by Barbara Walters, and as the subject of Fortune, New York Times, and Wall Street Journal cover articles.